N-tert-butylpiperidine-4-carboxamide → HCID 86706545, compound

Participants

Reaction Steps

The title compound is prepared according to the reactions described for BB-5 above starting from 3-methoxy-5-nitro-benzaldehyde and piperidine-4-carboxylic acid tert-butylamide yielding after reductive amination 1-(3-methoxy-5-nitro-benzyl)-piperidine-4-carboxylic acid tert-butylamide; LC-MS A: tR=0.63 min; [M+H]+=350.14 followed by reduction with stannous chloride the title compound; LC-MS A: tR=0.50 min; [M+H]+=320.19.

Provenance & Evidence