HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethyl-3-nitrobenzaldehyde → HCID 131736803, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethyl-3-nitrobenzaldehyde | HCID 2060457 | — |
| Reactant | N-tert-butylpiperidine-4-carboxamide | HCID 7175833 | — |
| Reactant | HCID 131736804 | HCID 131736804 | — |
| Product | HCID 131736803 | HCID 131736803 | — |
Reaction Steps
The title compound is prepared according to the reactions described for BB-5 above starting from 4-ethyl-3-nitro-benzaldehyde and piperidine-4-carboxylic acid tert-butylamide yielding after reductive amination 1-(4-ethyl-3-nitro-benzyl)-piperidine-4-carboxylic acid tert-butylamide; LC-MS A: tR=0.67 min; [M+H]+=348.18 followed by reduction with stannous chloride the title compound; LC-MS A: tR=0.53 min; [M+H]+=318.22.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428456B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-193694323ad743f6ab847265ff1e293d |
| Source note | uspto-grants-2016_08 |