HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → 4-Methyl-piperidine-4-carboxylic acid cyclohexylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | N-Cyclohexyl 1-boc-piperidine-4-carboxamide | HCID 4273089 | — |
| Reactant | 1-[(Tert-butoxy)carbonyl]-4-methylpiperidine-4-carboxylic acid | HCID 23282848 | — |
| Product | 4-Methyl-piperidine-4-carboxylic acid cyclohexylamide | HCID 63121587 | — |
Reaction Steps
The title compound is prepared according to the reaction sequence 3.01a-2.01b described above using 1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid instead of 1-(tert-butoxycarbonyl)-piperidine-4-carboxylic acid and cyclohexylamine instead of cyclohexylamine as in 3.01a: LC-MS A: tR=0.50 min; [M+H]+=225.17.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428456B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-709b89e505a947ea8d61124238a548c7 |
| Source note | uspto-grants-2016_08 |