Triethylamine → HCID 90418291, compound

Participants

Reaction Conditions

Reaction Steps

2-Chloropyrimidine-5-carboxylic acid (500 mg, 3.15 mmol), Et3N (1.15 mL, 8.20 mmol) and 4-aminotetrahydropyran (335 mg, 3.31 mmol) were dissolved in dioxane (10 mL) and heated in a microwave reactor at 150° C. for 30 min. The reaction mixture was concentrated in vacuo to give the crude title compound (701 mg) as a beige solid. LCMS (ES+): 224.1 [MH]+.

Provenance & Evidence