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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1486871Generated: October 30, 2026

Trifluoroacetic acid → HCID 178512535, compound

https://huagongshe.com/reaction/1486871

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178451063HCID 178451063—
ProductHCID 178512535HCID 178512535—

Reaction Steps

A mixture of 3-(5,5-bis(2-tert-butoxy-2-oxoethyl)-4,5-dihydro-1,2-oxazol-3-yl)-4-(1-(4-tert-butoxy-4-oxobutanoyl)piperidin-4-yl)phenyl 4-carbamimidamidobenzoate (29.2 mg) and TFA (1 mL) was stirred at room temperature for 2 hours. The reaction mixture was concentrated under reduced pressure, and then, the residue was washed with diethyl ether to obtain the title compound (25.4 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428470B2
Source datasetuspto-grants-2016_08
ORD IDord-85a84da6710d4645ab8b198426fefdbc
Source noteuspto-grants-2016_08