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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1486890Generated: November 3, 2026

Trifluoroacetic acid → HCID 178512544, compound

https://huagongshe.com/reaction/1486890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178450926HCID 178450926—
ProductHCID 178512544HCID 178512544—

Reaction Steps

A mixture of tert-butyl 5-(2-tert-butoxy-2-oxoethyl)-3-(3-(3-tert-butoxy-3-oxopropyl)-5-((4-carbamimidamidobenzoyl)oxy)phenyl)-4,5-dihydro-1,2-oxazole-5-carboxylate (104 mg) and TFA (2 mL) was stirred overnight at room temperature. The reaction mixture was concentrated under reduced pressure, and then, the residue was washed with diethyl ether to obtain the title compound (70.0 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428470B2
Source datasetuspto-grants-2016_08
ORD IDord-db846463daeb4b4199004d9a41f4e961
Source noteuspto-grants-2016_08