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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1486908Generated: October 30, 2026

HCID 118292783, compound → HCID 118292856, compound

https://huagongshe.com/reaction/1486908

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 118292783HCID 118292783—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 118292856HCID 118292856115.6%

Reaction Steps

A mixture of benzyl 1-(3-(2-(5,5-bis(2-(benzyloxy)-2-oxoethyl)-4,5-dihydro-1,2-oxazol-3-yl)-4-((4-nitrobenzoyl)oxy)phenyl)propanoyl)piperidine-4-carboxylate (939 mg), 10% Pd/C (containing about 55% water, 100 mg), and THF (10 mL) was stirred at room temperature for 4 hours under a hydrogen atmosphere. The catalyst was filtered off, and then, the filtrate was concentrated under reduced pressure to obtain the title compound (716 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428470B2
Source datasetuspto-grants-2016_08
ORD IDord-8f5d1ab4cd7b4fc388ad794f00c0287f
Source noteuspto-grants-2016_08