HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 118292783, compound → HCID 118292856, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 118292783 | HCID 118292783 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 118292856 | HCID 118292856 | 115.6% |
Reaction Steps
A mixture of benzyl 1-(3-(2-(5,5-bis(2-(benzyloxy)-2-oxoethyl)-4,5-dihydro-1,2-oxazol-3-yl)-4-((4-nitrobenzoyl)oxy)phenyl)propanoyl)piperidine-4-carboxylate (939 mg), 10% Pd/C (containing about 55% water, 100 mg), and THF (10 mL) was stirred at room temperature for 4 hours under a hydrogen atmosphere. The catalyst was filtered off, and then, the filtrate was concentrated under reduced pressure to obtain the title compound (716 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428470B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-8f5d1ab4cd7b4fc388ad794f00c0287f |
| Source note | uspto-grants-2016_08 |