Morpholine, 4-(3-methoxy-4-nitrophenyl)- → 2-Methoxy-4-morpholinoaniline

Participants

Reaction Steps

To a suspension of 4-(3-methoxy-4-nitrophenyl)morpholine (100 g, 0.42 mol) in tetrahydrofuran (2 L) was added palladium on carbon (10%, 10 g). The mixture was stirred under an atmosphere of hydrogen for 12 hours. The catalyst was removed by filtration and the filtrate was evaporated to afford the product 2-methoxy-4-morpholinoaniline (87 g, yield 100%).

Provenance & Evidence