2-Butyl-4-chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine → 2-Butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

HRID 1487249Notes

Reaction equation

HRID 1487249 reaction equation
[CH2:1]([C:5]1[N:6]=[C:7]([Cl:15])[C:8]2[NH:13][CH:12]=[C:11]([I:14])[C:9]=2[N:10]=1)[CH2:2][CH2:3][CH3:4].[CH2:16](C1N=C(Cl)C2NC(C)=CC=2N=1)CCC>>[CH2:1]([C:5]1[N:6]=[C:7]([Cl:15])[C:8]2[NH:13][C:12]([CH3:16])=[C:11]([I:14])[C:9]=2[N:10]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 1183828472-Butyl-4-chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidineHCID 1184166922-Butyl-4-chloro-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

Product 1

HCID 1184166162-Butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

Procedure

Prepared similarly to Intermediate 4 from. 2-butyl-4-chloro-6-methyl-5H-pyrrolo[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-d0e84b2d93fa4076a1369dc7fdf3fc50
Source dataset
uspto-grants-2016_08
Patent number
US09428512B2

Reaction notes

Loading…