HCID 118453817, compound → HCID 118453790, compound

Participants

Reaction Steps

A solution of 4-(4-amino-5-((benzyloxy)methyl)-2-butyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)but-3-yn-1-ol (948 mg, 2.505 mmol) in ethyl acetate (50 mL) and ethanol (50 mL) was hydrogenated using the H-cube (settings: 25° C., Full H2, 1 mL/min flow rate) and 10% Pd/C CatCart 70 as the catalyst. The reaction mixture was concentrated in vacuo at 60° C. to give the title compound as a viscous yellow oil which crystallised on standing (884 mg).

Provenance & Evidence