Thionyl Chloride → HCID 136360831, compound

Participants

Reaction Conditions

Reaction Steps

5-(hydroxymethyl)-4-(1H-imidazol-2-yl)-2-methylpyridin-3-ol (5.1 g, 25 mmol) was suspended in toluene (100 mL) and thionyl chloride (25 mL) was added. The suspension was heated to reflux for 2 h, cooled to 0° C. and filtered. The title compound was obtained as brown solid (Purity by NMR: 70-80%) and was used without further purification in the next step.

Provenance & Evidence