3-Methoxy-N-(1-methylazetidin-3-yl)-4-nitrobenzamide → 4-Amino-3-methoxy-N-(1-methylazetidin-3-yl)benzamide

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-methoxy-N-(1-methylazetidin-3-yl)-4-nitrobenzamide (1 equiv) and 10% palladium on carbon was stirred in a mixture of MeOH/THF under a hydrogen atmosphere. The mixture was stirred at 50° C. for 2 h. The reaction mixture was filtered and the filtrate was evaporated under reduced pressure to give the desired product (99% yield) as a white solid. MS (ESI) m/z 236.1 [M+H]+.

Provenance & Evidence