HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Aminobenzothiazole → 4-Nitrophenyl benzo[d]thiazol-6-ylcarbamate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Aminobenzothiazole | HCID 68288 | — |
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Nitrophenyl benzo[d]thiazol-6-ylcarbamate hydrochloride | HCID 66797303 | 81% |
Reaction Steps
6-Aminobenzothiazole (100 mg, 0.666 mmol) and p-nitrophenyl chloroformate (148 mg, 0.733 mmol) were stirred at rt in CH2Cl2 (5 mL) overnight. The resulting solid was collected by filtration, yielding 183 mg (81%) of the title compound. LC-MS: RT=8.17 min, [M+H]+=316.0
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428522B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-57ea033f27ed4484a37500e4707eb598 |
| Source note | uspto-grants-2016_08 |