5-Bromo-2-methylbenzoic acid → HCID 82052158, compound

HRID 1487867Notes

Reaction equation

HRID 1487867 reaction equation
C1([C:4]2[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=2[C:13](=[O:16])[CH2:14][CH3:15])CC1.Br[C:18]1C=CC(C)=C(C=1)C(O)=O.BrC1C=C(C=CC=1C1CC1)C(O)=O>>[CH3:18][C:11]1[CH:12]=[CH:4][C:5]([C:13](=[O:16])[CH2:14][CH3:15])=[CH:6][C:7]=1[C:8]([OH:10])=[O:9]

Participants

4

Reactant 3

HCID 3460045-Bromo-2-methylbenzoic acidHCID 448285263-Bromo-4-cyclopropylbenzoic acidHCID 90021739HCID 90021739, compound

Product 1

HCID 82052158HCID 82052158, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 10.6, except 5-bromo-2-methylbenzoic acid was used in place of 3-bromo-4-cyclopropylbenzoic acid (compound 10.3).

Sources & evidence

ORD record
ord-65b1ca841f43481586bd1a42e11494a5
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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