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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1487882Generated: October 31, 2026

4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) → HCID 178425809, compound

https://huagongshe.com/reaction/1487882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1)HCID 19391618—
Reactant4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochlorideHCID 90021334—
ReactantHCID 178425891HCID 178425891—
ReactantHCID 178494679HCID 178494679—
ProductHCID 178425809HCID 178425809—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 27, except 3-(4-chloro-2-(hydroxymethyl)-1H-imidazol-5-yl)-4-methylbenzoic acid (compound 28.1) was used in place of 3-(4-chloro-2-(methoxymethyl)-1H-imidazol-5-yl)-4-methylbenzoic acid (compound 27.5) and 4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochloride (compound 43.4) was used in place of 4-(piperidin-4-yl)benzonitrile hydrochloride (compound 1.2). m/z (ES+) 425 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-3372b898946749b7a295cd00c75b0b62
Source noteuspto-grants-2016_08