HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) → HCID 178425809, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) | HCID 19391618 | — |
| Reactant | 4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochloride | HCID 90021334 | — |
| Reactant | HCID 178425891 | HCID 178425891 | — |
| Reactant | HCID 178494679 | HCID 178494679 | — |
| Product | HCID 178425809 | HCID 178425809 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 27, except 3-(4-chloro-2-(hydroxymethyl)-1H-imidazol-5-yl)-4-methylbenzoic acid (compound 28.1) was used in place of 3-(4-chloro-2-(methoxymethyl)-1H-imidazol-5-yl)-4-methylbenzoic acid (compound 27.5) and 4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochloride (compound 43.4) was used in place of 4-(piperidin-4-yl)benzonitrile hydrochloride (compound 1.2). m/z (ES+) 425 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-3372b898946749b7a295cd00c75b0b62 |
| Source note | uspto-grants-2016_08 |