HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetamidine monohydrochloride → HCID 178432859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetamidine monohydrochloride | HCID 67170 | — |
| Reactant | 2-Methoxyethanimidamide hydrochloride | HCID 13548602 | — |
| Reactant | Methyl 3-iodo-4-methylbenzoate | HCID 13614033 | — |
| Reactant | 4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) | HCID 19391618 | — |
| Reactant | Methyl 5-iodo-2,4-dimethylbenzoate | HCID 44828936 | — |
| Reactant | 4-(Azetidin-3-yl)benzonitrile hydrochloride | HCID 55254991 | — |
| Product | HCID 178432859 | HCID 178432859 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for preparation of compound 27, except methyl 5-iodo-2,4-dimethylbenzoate (compound 31.1) was used in place of methyl 3-iodo-4-methylbenzoate (compound 5.3), acetimidamide hydrochloride was used in place of 2-methoxyacetimidamide (compound 4.7) and 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2) was used in place of 4-(piperidin-4-yl)benzonitrile hydrochloride (compound 1.2). m/z (ES+) 405 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-0b0adbe8f5244565bace0d62b74d62d6 |
| Source note | uspto-grants-2016_08 |