Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate → Tert-butyl 4-(imidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate

HRID 1487890Notes

Reaction equation

HRID 1487890 reaction equation
C([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)#N.BrC1C=C[N:26]2[CH:29]=[N:30]C=C2C=1>>[CH:3]1[N:26]=[CH:29][N:30]2[CH:4]=[CH:5][C:6]([CH:9]3[CH2:10][CH2:11][N:12]([C:15]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:16])[CH2:13][CH2:14]3)=[CH:7][C:8]=12

Participants

3

Reactant 2

HCID 22492960Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylateHCID 668886407-Bromoimidazo(1,5-a)pyridine2×

Product 1

HCID 90033879Tert-butyl 4-(imidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.1, except 7-bromoimidazo[1,5-a]pyridine (compound 39.3) was used in place of 4-bromobenzonitrile.

Sources & evidence

ORD record
ord-b643fa1f81dd445cabd05bd9feed9306
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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