HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Iodo-2,4-dimethylbenzoic acid → Methyl 4-cyclopropyl-5-(1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepin-2-yl)-2-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Iodo-2,4-dimethylbenzoic acid | HCID 23091875 | — |
| Reactant | 4-Cyclopropyl-5-iodo-2-methylbenzoic acid | HCID 90020958 | — |
| Reactant | HCID 90066696 | HCID 90066696 | — |
| Product | Methyl 4-cyclopropyl-5-(1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepin-2-yl)-2-methylbenzoate | HCID 90066729 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 83.4, except 4-cyclopropyl-5-iodo-2-methylbenzoic acid (compound 86.3) was used in place of 5-iodo-2,4-dimethylbenzoic acid (compound 1.3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-84c9d6f7c3134d0195863188d1abc848 |
| Source note | uspto-grants-2016_08 |