4-Fluoro-2-methylbenzoic acid → 4-Fluoro-5-iodo-2-methylbenzoic acid

HRID 1487990Notes

Reaction equation

HRID 1487990 reaction equation
[I:1][C:2]1[C:3](C)=[CH:4][C:5]([CH3:11])=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].[F:13]C1C=CC(C(O)=O)=C(C)C=1>>[F:13][C:3]1[C:2]([I:1])=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([CH3:11])[CH:4]=1

Participants

3

Reactant 2

HCID 38606394-Fluoro-2-methylbenzoic acidHCID 230918755-Iodo-2,4-dimethylbenzoic acid

Product 1

HCID 900215604-Fluoro-5-iodo-2-methylbenzoic acid

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.3, except 4-fluoro-2-methylbenzoic acid was used in place of 2,4-dimethylbenzoic acid.

Sources & evidence

ORD record
ord-e6d09feb72374095b001d4825e1a0522
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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