HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-cyano-4-cyclobutyl-2-methylbenzoate → Methyl 5-cyano-4-fluoro-2-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-cyano-4-cyclobutyl-2-methylbenzoate | HCID 68288299 | — |
| Reactant | Methyl 4-cyclobutyl-5-iodo-2-methylbenzoate | HCID 68288363 | — |
| Reactant | Methyl 4-fluoro-5-iodo-2-methylbenzoate | HCID 90021566 | — |
| Product | Methyl 5-cyano-4-fluoro-2-methylbenzoate | HCID 90021743 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 6.4, except methyl 4-fluoro-5-iodo-2-methylbenzoate (compound 101.2) was used in place of methyl 4-cyclobutyl-5-iodo-2-methylbenzoate (compound 6.3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-f6b5b83a7cd54023801ce8f946bf6df2 |
| Source note | uspto-grants-2016_08 |