4-Fluoro-3-iodobenzoic acid → Methyl 4-fluoro-3-iodobenzoate

HRID 1487995Notes

Reaction equation

HRID 1487995 reaction equation
Br[C:2]1C=CC(C(OC)=O)=C(C)C=1.[F:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][C:15]=1[I:23]>>[F:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([O:20][CH3:2])=[O:19])=[CH:16][C:15]=1[I:23]

Participants

3

Reactant 2

HCID 103614-Fluoro-3-iodobenzoic acidHCID 22031226Methyl 4-bromo-2-methylbenzoate

Product 1

HCID 53421332Methyl 4-fluoro-3-iodobenzoate

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 6.1, except 4-fluoro-3-iodobenzoic acid was used in place of 4-bromo-2-methylbenzoic acid.

Sources & evidence

ORD record
ord-36ac684d50a34eb18224171056a5edb5
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

Loading…