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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1487996Generated: November 1, 2026

Methyl 4-fluoro-3-iodobenzoate → Methyl 3-(2-bromoacetyl)-4-fluorobenzoate

https://huagongshe.com/reaction/1487996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-fluoro-3-iodobenzoateHCID 53421332—
ReactantMethyl 3-(2-bromoacetyl)-4-methylbenzoateHCID 90021973—
ReactantMethyl 3-(2-(methoxymethyl)-1H-imidazol-5-yl)-4-methylbenzoateHCID 90030068—
ProductMethyl 3-(2-bromoacetyl)-4-fluorobenzoateHCID 90021814—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 27.3, except methyl 4-fluoro-3-iodobenzoate (compound 132.1) was used in place of methyl 3-(2-bromoacetyl)-4-methylbenzoate (compound 27.2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-348c6faadc144883a47ba00c9c28fc86
Source noteuspto-grants-2016_08