HCID 178432711, compound → HCID 178424669, compound

HRID 1488015Notes

Reaction equation

HRID 1488015 reaction equation
CC1NC(C2C=C(C=CC=2C)C(O)=O)=C(C)N=1.[CH:18]1([C:21]2[NH:22][C:23]([C:27]3[C:28]([CH3:38])=[CH:29][C:30]([CH3:37])=[C:31]([CH:36]=3)[C:32]([O:34]C)=[O:33])=[C:24]([CH3:26])[N:25]=2)[CH2:20][CH2:19]1.CC1NC(C2C=C(C=CC=2C)C(OC)=O)=C(C)N=1>>[CH:18]1([C:21]2[NH:22][C:23]([C:27]3[C:28]([CH3:38])=[CH:29][C:30]([CH3:37])=[C:31]([CH:36]=3)[C:32]([OH:34])=[O:33])=[C:24]([CH3:26])[N:25]=2)[CH2:20][CH2:19]1

Participants

4

Reactant 3

HCID 178432711HCID 178432711, compoundHCID 178497336HCID 178497336, compound2×HCID 178497719HCID 178497719, compound

Product 1

HCID 178424669HCID 178424669, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5.7, except methyl 5-(2-cyclopropyl-4-methyl-1H-imidazol-5-yl)-2,4-dimethylbenzoate (compound 160.3) was used in place of methyl 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoate (compound 5.6). m/z (ES+) 271 (M+H)+.

Sources & evidence

ORD record
ord-9314ed30457d428f90e6719499b2dcec
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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