HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Azetidin-3-yl)benzonitrile hydrochloride → HCID 178425808, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Azetidin-3-yl)benzonitrile hydrochloride | HCID 55254991 | — |
| Reactant | 4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochloride | HCID 90021334 | — |
| Reactant | 2,4-Dimethyl-5-(4-methyl-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)benzoic acid | HCID 90029976 | — |
| Reactant | HCID 178425884 | HCID 178425884 | — |
| Product | HCID 178425808 | HCID 178425808 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 164, except 4-methyl-3-(4-methyl-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)benzoic acid (compound 168.1) was used in place of 2,4-dimethyl-5-(4-methyl-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)benzoic acid (compound 164.2) and 4-(3-fluoroazetidin-3-yl)benzonitrile hydrochloride (compound 43.4) was used in place of 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2). m/z (ES+) 459 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-6139fb7697a341b08b294242dde1f933 |
| Source note | uspto-grants-2016_08 |