Methylglyoxal → HCID 178430849, compound

HRID 1488032Notes

Reaction equation

HRID 1488032 reaction equation
CC1[NH:3][CH:4]=[C:5]([C:7](F)(F)F)[N:6]=1.[CH3:11][C:12]1([CH:16]=O)[CH2:15][O:14][CH2:13]1.O=C(C)C=O.FC(F)(F)C(=O)C=O>>[CH3:7][C:5]1[N:6]=[C:16]([C:12]2([CH3:11])[CH2:15][O:14][CH2:13]2)[NH:3][CH:4]=1

Participants

5

Reactant 4

HCID 880MethylglyoxalHCID 27790243,3,3-Trifluoro-2-oxopropanalHCID 189624683-Methyloxetane-3-carbaldehydeHCID 178432834HCID 178432834, compound

Product 1

HCID 178430849HCID 178430849, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 16.2, except 3-methyloxetane-3-carbaldehyde was used in place of acetaldehyde and 2-oxopropanal was used in place of 3,3,3-trifluoro-2-oxopropanal (compound 16.1). m/z (ES+) 153 (M+H)+.

Sources & evidence

ORD record
ord-28757f6d998c46fcbd7e2bc497fd1679
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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