HCID 178432711, compound → HCID 178425882, compound

HRID 1488038Notes

Reaction equation

HRID 1488038 reaction equation
CC1NC(C2C=C(C=CC=2C)C(O)=O)=C(C)N=1.[CH3:18][C:19]1[CH:28]=[CH:27][C:22]([C:23]([O:25]C)=[O:24])=[CH:21][C:20]=1[C:29]1[NH:33][C:32]([C:34]2([CH3:38])[CH2:37][O:36][CH2:35]2)=[N:31][C:30]=1[CH3:39].CC1NC(C2C=C(C=CC=2C)C(OC)=O)=C(C)N=1>>[CH3:18][C:19]1[CH:28]=[CH:27][C:22]([C:23]([OH:25])=[O:24])=[CH:21][C:20]=1[C:29]1[NH:33][C:32]([C:34]2([CH3:38])[CH2:35][O:36][CH2:37]2)=[N:31][C:30]=1[CH3:39]

Participants

4

Reactant 3

HCID 178432711HCID 178432711, compoundHCID 178497713HCID 178497713, compound2×HCID 178497719HCID 178497719, compound

Product 1

HCID 178425882HCID 178425882, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5.7, except methyl 4-methyl-3-(4-methyl-2-(3-methyloxetan-3-yl)-1H-imidazol-5-yl)benzoate (compound 177.1) was used in place of methyl 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoate (compound 5.6). m/z (ES+) 287 (M+H)+.

Sources & evidence

ORD record
ord-394b3d8b37a2471fa514fa3192424a81
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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