HCID 178432711, compound → HCID 178424678, compound

HRID 1488043Notes

Reaction equation

HRID 1488043 reaction equation
CC1NC(C2C=C(C=CC=2C)C(O)=O)=C(C)N=1.[CH3:18][C:19]1[CH:28]=[C:27]([CH3:29])[C:26]([C:30]2[NH:34][C:33]([CH:35]3[CH2:38][O:37][CH2:36]3)=[N:32][C:31]=2[CH3:39])=[CH:25][C:20]=1[C:21]([O:23]C)=[O:22].CC1NC(C2C=C(C=CC=2C)C(OC)=O)=C(C)N=1>>[CH3:18][C:19]1[CH:28]=[C:27]([CH3:29])[C:26]([C:30]2[NH:34][C:33]([CH:35]3[CH2:38][O:37][CH2:36]3)=[N:32][C:31]=2[CH3:39])=[CH:25][C:20]=1[C:21]([OH:23])=[O:22]

Participants

4

Reactant 3

HCID 178432711HCID 178432711, compoundHCID 178497347HCID 178497347, compound2×HCID 178497719HCID 178497719, compound

Product 1

HCID 178424678HCID 178424678, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5.7, except methyl 2,4-dimethyl-5-(4-methyl-2-(oxetan-3-yl)-1H-imidazol-5-yl)benzoate (compound 180.3) was used in place of methyl 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoate (compound 5.6). m/z (ES+) 287 (M+H)+.

Sources & evidence

ORD record
ord-3a7c457a0f024f36baf2f532bca25be4
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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