tert-Butyl 4-formylpiperidine-1-carboxylate → HCID 178432594, compound

HRID 1488045Notes

Reaction equation

HRID 1488045 reaction equation
[I:1][C:2]1[NH:6][C:5]([CH:7]([CH3:9])[CH3:8])=[N:4][C:3]=1[CH3:10].C(C1C[CH2:17][N:16]([C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH2:15]C1)=O>>[I:1][C:2]1[NH:6][C:5]([CH:7]2[CH2:9][CH2:17][N:16]([C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH2:15][CH2:8]2)=[N:4][C:3]=1[CH3:10]

Participants

3

Reactant 2

HCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylateHCID 178432758HCID 178432758, compound

Product 1

HCID 178432594HCID 178432594, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 159.2, except tert-butyl 4-formylpiperidine-1-carboxylate was used in place of isobutyraldehyde. m/z (ES+) 392 (M+H)+.

Sources & evidence

ORD record
ord-f3df5e2692784afca156bf4f544b808b
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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