HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) → HCID 178425796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)benzonitrile--hydrogen chloride (1/1) | HCID 19391618 | — |
| Reactant | 4-(Azetidin-3-yl)benzonitrile hydrochloride | HCID 55254991 | — |
| Reactant | HCID 178497363 | HCID 178497363 | — |
| Reactant | HCID 178497723 | HCID 178497723 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178425796 | HCID 178425796 | — |
Reaction Steps
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1, except methyl 4-methyl-3-(4-methyl-2-(pyrrolidin-1-yl)-1H-imidazol-5-yl)benzoate (compound 197.3) was used in place of methyl 5-(2,4-dimethyl-1H-imidazol-5-yl)-2,4-dimethylbenzoate (compound 1.7) and 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2) was used in place of 4-(piperidin-4-yl)benzonitrile hydrochloride (compound 1.2). m/z (ES+) 426 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428502B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-72110a1c4dc945578559086c82962951 |
| Source note | uspto-grants-2016_08 |