HCID 178421679, compound → HCID 178421678, compound

HRID 1488081Notes

Reaction equation

HRID 1488081 reaction equation
[I:1]C1NC(C2(C)COC2)=NC=1C.[CH3:13][C:14]1([C:18]2[NH:19][CH:20]=[C:21]([C:23]([F:26])([F:25])[F:24])[N:22]=2)[CH2:17][O:16][CH2:15]1.CC1N=C(C2(C)COC2)NC=1>>[I:1][C:20]1[NH:19][C:18]([C:14]2([CH3:13])[CH2:17][O:16][CH2:15]2)=[N:22][C:21]=1[C:23]([F:26])([F:24])[F:25]

Participants

4

Reactant 3

HCID 178421679HCID 178421679, compound2×HCID 178430849HCID 178430849, compoundHCID 178432598HCID 178432598, compound

Product 1

HCID 178421678HCID 178421678, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 175.2, except 2-(3-methyloxetan-3-yl)-4-(trifluoromethyl)-1H-imidazole (compound 202.1) was used in place of 4-methyl-2-(3-methyloxetan-3-yl)-1H-imidazole (compound 175.1). m/z (ES+) 333 (M+H)+.

Sources & evidence

ORD record
ord-60d694a83b2843208a4afa3526c68aed
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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