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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1488097Generated: October 30, 2026

4-(Azetidin-3-yl)benzonitrile hydrochloride → HCID 90033276, compound

https://huagongshe.com/reaction/1488097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Azetidin-3-yl)benzonitrile hydrochlorideHCID 55254991—
Reactant4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochlorideHCID 90021334—
ReactantHCID 90028965HCID 90028965—
ReactantHCID 178432711HCID 178432711—
ProductHCID 90033276HCID 90033276—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5, except 5-(4-cyano-2-(hydroxymethyl)-1H-imidazol-5-yl)-2,4-dimethylbenzoic acid (compound 219.6) was used in place of 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoic acid (compound 5.7) and 4-(3-fluoroazetidin-3-yl)benzonitrile hydrochloride (compound 43.4) was used in place of 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2). m/z (ES+) 430 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-76f4366c490940198516d18007476e52
Source noteuspto-grants-2016_08