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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1488106Generated: November 4, 2026

4-(Azetidin-3-yl)benzonitrile hydrochloride → HCID 178424686, compound

https://huagongshe.com/reaction/1488106

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Azetidin-3-yl)benzonitrile hydrochlorideHCID 55254991—
Reactant4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochlorideHCID 90021334—
ReactantHCID 178424683HCID 178424683—
ReactantHCID 178424688HCID 178424688—
ProductHCID 178424686HCID 178424686—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 222, except 5-(2-(hydroxymethyl)-4-methyl-1H-imidazol-5-yl)-2,4-dimethylbenzoic acid (compound 222.5) was used in place of 5-(2-(cyanomethyl)-4-methyl-1H-imidazol-5-yl)-2,4-dimethylbenzoic acid (compound 222.6) and 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2) was used in place of 4-(3-fluoroazetidin-3-yl)benzonitrile hydrochloride (compound 43.4). m/z (ES+) 401 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-8c08a095060b466681861cefe40fd61d
Source noteuspto-grants-2016_08