HCID 178432771, compound → HCID 178497717, compound

HRID 1488110Notes

Reaction equation

HRID 1488110 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:8]2[CH:9]=[C:10]([CH:15]=[CH:16][C:17]=2[CH3:18])[C:11]([O:13][CH3:14])=[O:12])=[C:5]([CH3:7])[N:6]=1.[CH2:19]([O:26][CH2:27]CC1NC(I)=C(C)N=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.IC1NC(C)=NC=1C>>[CH2:19]([O:26][CH2:27][CH2:1][C:2]1[NH:3][C:4]([C:8]2[CH:9]=[C:10]([CH:15]=[CH:16][C:17]=2[CH3:18])[C:11]([O:13][CH3:14])=[O:12])=[C:5]([CH3:7])[N:6]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 178432771HCID 178432771, compoundHCID 178432802HCID 178432802, compound2×HCID 178497719HCID 178497719, compound

Product 1

HCID 178497717HCID 178497717, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5.6, except 2-(2-(benzyloxy)ethyl)-5-iodo-4-methyl-1H-imidazole (compound 227.2) was used in place of 5-iodo-2,4-dimethyl-1H-imidazole (compound 5.5).

Sources & evidence

ORD record
ord-3edbb205f7ab4893a44f877d55d8ffd2
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

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