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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1488152Generated: November 1, 2026

4-(Azetidin-3-yl)benzonitrile hydrochloride → HCID 178424695, compound

https://huagongshe.com/reaction/1488152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Azetidin-3-yl)benzonitrile hydrochlorideHCID 55254991—
Reactant4-(3-Fluoroazetidin-3-yl)benzonitrile hydrochlorideHCID 90021334—
ReactantHCID 178424696HCID 178424696—
ReactantHCID 178432711HCID 178432711—
ProductHCID 178424695HCID 178424695—

Reaction Steps

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5, except 5-(3-chloro-4-methyl-1H-pyrazol-5-yl)-2,4-dimethylbenzoic acid (compound 250.6) was used in place of 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoic acid (compound 5.7) and 4-(3-fluoroazetidin-3-yl)benzonitrile hydrochloride (compound 43.4) was used in place of 4-(azetidin-3-yl)benzonitrile hydrochloride (compound 5.2). m/z (ES+) 423 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09428502B2
Source datasetuspto-grants-2016_08
ORD IDord-f31a47115c1c4c74869f11b49c497067
Source noteuspto-grants-2016_08