Tetrahydro-2H-pyran-4-carboxaldehyde → HCID 178506274, compound

HRID 1488220Notes

Reaction equation

HRID 1488220 reaction equation
[I:1][C:2]1[NH:6][C:5]([C:7]2([CH3:11])[CH2:10]OC2)=[N:4][C:3]=1[C:12]([F:15])([F:14])[F:13].[O:16]1[CH2:21]CC(C=O)C[CH2:17]1>>[I:1][C:2]1[NH:6][C:5]([CH:7]2[CH2:10][CH2:21][O:16][CH2:17][CH2:11]2)=[N:4][C:3]=1[C:12]([F:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 9964078Tetrahydro-2H-pyran-4-carboxaldehydeHCID 178421678HCID 178421678, compound

Product 1

HCID 178506274HCID 178506274, compound

Procedure

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 202.2, except tetrahydro-2H-pyran-4-carbaldehyde was used instead of 3-methyloxetane-3-carbaldehyde.

Sources & evidence

ORD record
ord-d9f25b57df144e33a2e1240a81980c84
Source dataset
uspto-grants-2016_08
Patent number
US09428502B2

Reaction notes

Loading…