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HRID1488244

反应详情

EQUATION

反应方程式

HRID 1488244 的结构方程式

REACTANTS

反应物

2
结构：[N-]=[N+]=NCCO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccccc2)[C@H](O[C@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@@H]2OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1
HCID118005661

未命名化合物

结构：CO[Na]
HCID178418582

未命名化合物

PRODUCTS

生成物

1
结构：[N-]=[N+]=NCCO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H]1O
HCID117995942

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

CONDITIONS

反应条件

温度
25 °C

PROCEDURE

实验过程

In a 50 mL round bottom flask was added 2-azidoethyl 2,4-di-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-α-D-mannopyranoside (350 mg, 0.338 mmol) and CH3OH (5 mL). To the above solution was added NaOCH3 (conc) dropwise till pH >10. The reaction mixture was allowed to stir at 25° C. for 6 hr. To the above solution was added Dowex H+(50W×8-200) resin till pH ˜7. The solid resin was filtered off and the filtrate was concentrated to give the title compound. LC-MS Method A: m/e=434.00 [M+1]; Rt=0.44 min.

WORKUP

后处理

  1. additionTo the above solution was added Dowex H+(50W×8-200) resin till pH ˜7
  2. filtrationThe solid resin was filtered off
  3. concentrationthe filtrate was concentrated