HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → Methyl (2-hydroxymethyl-5-methylphenoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Methyl (2-formyl-5-methylphenoxy)acetate | HCID 54288233 | — |
| Catalyst | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl (2-hydroxymethyl-5-methylphenoxy)acetate | HCID 54364037 | 82.9% |
Reaction Steps
By the method of Example 1, Step G, 11.27 g (0.054 mole) of methyl (2-formyl-5-methylphenoxy)acetate was reacted with 0.54 g (0.014 mole) of sodium borohydride and 0.10 g (0.0018 mole) of sodium methoxide in 30 of methanol, yielding 9.41 g of methyl (2-hydroxymethyl-5-methylphenoxy)acetate as a yellow oil. The NMR spectrum was consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05674810 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-36db8b60a59a4213866645b24ac47b71 |
| Source note | uspto-grants-1997_10 |