HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → Methyl 2-(4-formylphenoxy)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-bromopropionate | HCID 95576 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 2-(4-formylphenoxy)propanoate | HCID 18981016 | 71.5% |
Reaction Steps
By the method of Example 1, Step F, 10.0 g (0.0819 mole) of 4-hydroxybenzaldehyde and 16.4 g (0.0983 mole) of methyl 2-bromopropionate were reacted in the presence of 13.6 g (0.0983 mole) of anhydrous potassium carbonate in N,N-dimethylformamide, yielding 12.2 g of methyl 2-(4-formylphenoxy)propionate as a yellow liquid. The NMR and IR spectra were consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05674810 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-9556b6055bc74a98a021574b05c607b1 |
| Source note | uspto-grants-1997_10 |