Allyl bromide → N-(2-Methyl-2-propenyl)-4-acetamido-3-bromo-2,6-dimethylanisole

関与物質

反応手順

Treatment of 4-acetamido-3-bromo-2,6-dimethylanisole (2.7 g, 10 mmol) according to a procedure similar to the one used for making compound 8, substituting methallylbromide for allyl bromide, afforded 14 (2.8 g, 86% yield) as a viscous liquid. Spectral data: 1H NMR (250 MHz): δ 1.71 (s, 3H), 1.75 (s, 3H), 2.18 (s, 3H), 2.33 (s, 3H), 3.26 (d, 1H, J=15 Hz), 3.66 (s, 3H), 4.62 (s, 1H), 4.75 (s, 1H), 4.82 (d, 1H, J=15 Hz), 6.82 (s, 1H).

情報源と証拠