HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Acetyl-5-methoxy-3,3,4,6-tetramethylindoline → 1-Acetyl-3,3,4,6-tetramethyl-5-indolinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Acetyl-5-methoxy-3,3,4,6-tetramethylindoline | HCID 22905632 | — |
| Reactant | N-Acetyl-5-hydroxy-3,4,6-trimethylindoline | HCID 22905640 | — |
| Product | 1-Acetyl-3,3,4,6-tetramethyl-5-indolinol | HCID 382327 | 75% |
Reaction Steps
Treatment of 15 (741 mg, 3 mmol) according to a procedure similar that used for making 11a afforded 16 (524 mg, 75% yield) as a colorless solid, mp 173°-174° C. Spectral data: 13C NMR (CD3 SOCD3): δ 11.7, 17.3, 23.9, 27.0, 40.6, 63.7, 115.4, 121.1, 122.8, 135.6, 149.2, 167.2; HRMS: calcd. for C14H19NO2 233.1415, fnd. 233.1416. Anal: calcd. for C14H19NO2C, 72.08, N, 6.00, H, 8.20, fnd. C, 71.88, N, 5.95, H, 8.22.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05674876 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-1a0db94f8d7c439aba5aabe6db0ee7b2 |
| Source note | uspto-grants-1997_10 |