Potassium Carbonate → HCID 22906436, compound

Participants

Reaction Steps

3.60 g (0.02 moles plus 0.14 g excess) of 4-nitrophthalonitrile was dissolved in 50 ml anhydrous DMSO in a 100 ml three-necked flask fitted with a magnetic stirrer bar under nitrogen. 1.28 g (0.01 moles) of 3-fluorocatechol (Aldrich) was added to the mixture followed by 5 g of anhydrous potassium carbonate. The mixture was stirred at room temperature for 24 hours. The workup was as described in Example 5 and yielded 3.04 g of off-white crystals of the title compound (80% theoretical yield). The product had the formula: ##STR15## The melting point was 198.5°-199.5° C. The elemental analysis for C22H9FN4O2 was calc.: C, 69.47%; H, 2.36%; N, 14.73%; found: C, 69.47%; H, 2.34%; N, 14.80%.

Provenance & Evidence