HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → HCID 21460685, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 21460705 | HCID 21460705 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21460685 | HCID 21460685 | — |
Reaction Steps
Suspend the 3-amino-2-carbethoxy-6-nitroindole (0.6 mmol) in tetrahydrofuran (mL) and add triethylamine (0.62 mmol). Add benzoyl chloride (0.62 mmol) and stir for 30 minutes at room temperature. Dilute the reaction with ethyl acetate, rinse with 1M HCl, water, dry over magnesium sulfate, filter and concentrate in vacuo. Recrystallize from hot ethyl acetate/hexane to yield 3-[(phenacyl)amino]-2-carbethoxy-6-nitroindole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05675018 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-5955d19d566f4bb7a9f4bf98ec498d53 |
| Source note | uspto-grants-1997_10 |