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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1488817Generated: November 3, 2026

Trifluoroacetic acid → HCID 57279336, compound

https://huagongshe.com/reaction/1488817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 21460758HCID 21460758—
SolventDichloromethaneHCID 6344—
SolventEthyl AcetateHCID 8857—
ProductHCID 57279336HCID 57279336—

Reaction Steps

Dissolve 3-[(phenacyl)methylamino]-2-carbethoxy-6-nitro-1-(tert-butyloxycarbonyl)-indole from above in methylene chloride. Add excess trifluoracetic acid and stir overnight at room temperture. Concentrate the reaction in vacuo, dilute with ethyl acetate and rinse with saturated sodium bicarbonate, dry over magnesium sulfate, filter and concentrate in vacuo to yield 3-[(phenacyl)methylamino]-2-carbethoxy-6-nitroindole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05675018
Source datasetuspto-grants-1997_10
ORD IDord-8ff006c2e6944bdebae94ec25436cc5b
Source noteuspto-grants-1997_10