Ammonia → HCID 178508669, compound

Participants

Reaction Steps

To 180 ml of methanol were fed 20 g of a phthalonitrile represented by the formula (XV) and 14 g of sodium methoxide. The mixture was stirred at room temperature for 1 hour while blowing ammonia gas thereinto and, then, refluxed with heating for 3 hours with stirring while blowing ammonia gas thereinto. After being cooled to room temperature, the resulting mixture was concentrated as much as possible. The concentrate was dissolved in 700 ml of chloroform and was washed well with water and with hot water. Water in the organic layer was removed with magnesium sulfate and toluene was removed by distillation. The residue was recrystallized from hexane to obtain 19.7 g (yield: 91.7%) of a compound having the following formula (XVI). ##STR38##

Provenance & Evidence