HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 2-nitro-4-fluoro-5-(4-oxo-4H-pyridin-1-yl)-aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 5-Chloro-4-fluoro-2-nitroaniline | HCID 517835 | — |
| Reactant | HCID 178418642 | HCID 178418642 | — |
| Product | 2-nitro-4-fluoro-5-(4-oxo-4H-pyridin-1-yl)-aniline | HCID 22903584 | 22.6% |
Reaction Steps
First, 3.811 g of 2-nitro-4-fluoro-5-chloroaniline, 2.473 g of 4-hydroxypyridine, and 1.827 g of powdered potassium hydroxide were allowed to react at 130° C. for 3 hours in a nitrogen atmosphere in the same way as in Reference Example 1 to give 1.125 g of 2-nitro-4-fluoro-5-(4-oxo-4H-pyridin-1-yl)-aniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677305 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-4c547b1d020a47fa802a7c274e241185 |
| Source note | uspto-grants-1997_10 |