Potassium Hydroxide → HCID 22903585, compound

Participants

Reaction Conditions

Reaction Steps

First, a mixture containing 3.0 g of 3-chloro-4-dimethylsulfamoyl-6-nitroaniline, 1.39 g of 4-hydroxypyridine, 0.91 g of 86% potassium hydroxide, and 20 ml of dimethylsulfoxide was heated in an oil bath at 130° C. for 1.5 hours. The subsequent processes were conducted in the same way as in Reference Example 3 to give 1.675 g of 4-dimethylsulfamoyl-3-(4-oxo-4H-pyridin-1-yl)-6-nitroaniline.

Provenance & Evidence