HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-2,3-dihydro-4-fluoro-1H-inden-1-one → 2-Bromo-6,7-dichloro-1-indanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-2,3-dihydro-4-fluoro-1H-inden-1-one | HCID 9837493 | — |
| Reactant | 4,5-dichloro-2,3-dihydro-1H-inden-1-one | HCID 22903622 | — |
| Reactant | 2-Bromo-4,5-dichloro-1-indanone | HCID 22903628 | — |
| Catalyst | Copper bromide (CuBr2) | HCID 24611 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Bromo-6,7-dichloro-1-indanone | HCID 22903602 | — |
Reaction Steps
The 2-bromo-4,5-dichloro-1-indanone can be prepared as in Example 14 for the preparation of 2-bromo-4-fluoro-1-indanone but starting with 12.67 g of 4,5-dichloro-1-indanone, 37.3 g of copper bromide and 400 ml of dioxane. 16.79 g of 2-bromo-6,7-dichloro-1-indanone are thus obtained which melt at 131° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677306 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-35da252a3bbb48d082e25dc7d04b829f |
| Source note | uspto-grants-1997_10 |