HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-2,3-dihydro-4-fluoro-1H-inden-1-one → 2-Bromo-4,6-dichloro-1-indanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-2,3-dihydro-4-fluoro-1H-inden-1-one | HCID 9837493 | — |
| Reactant | 4,6-Dichloro-1-indanone | HCID 12206518 | — |
| Catalyst | Copper bromide (CuBr2) | HCID 24611 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Bromo-4,6-dichloro-1-indanone | HCID 12206524 | — |
Reaction Steps
The 2-bromo-4,6-dichloro-1-indanone is prepared as in Example 14 for the preparation of 2-bromo-4-fluoro-1-indanone but starting with 21.6 g of 4,6-dichloro-1-indanone, 63.56 g of copper bromide and 690 ml of dioxane. 14.5 g of 2-bromo-4,6-dichloro-1-indanone are obtained which melt at 80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677306 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-fa248855844946139a2b36b84e6193f0 |
| Source note | uspto-grants-1997_10 |