HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (1-azabicyclo[2.2.2]octan-3-ylidene)cyanoacetate → HCID 15379686, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (1-azabicyclo[2.2.2]octan-3-ylidene)cyanoacetate | HCID 54445383 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15379686 | HCID 15379686 | — |
Reaction Steps
A solution of ethyl (1-azabicyclo[2.2.2]octan-3-ylidene)cyanoacetate (73 g, 0.33 mmol) in absolute ethanol (1 l) was treated with 10% palladium on charcoal (10 g) and hydrogen in a parr shaker at 20 psi for 5 h. Filtration and evaporation gave the wanted product in 68 g yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677313 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-a1de0ec75dd7403ab7e7abdab7efabbf |
| Source note | uspto-grants-1997_10 |