HCID 22903660, compound → HCID 22903668, compound

HRID 1489158Notes

Reaction equation

HRID 1489158 reaction equation
C([N:8]1[CH2:12][CH2:11][C:10]([CH2:15][NH:16]CC2C=CC=CC=2)([CH2:13][OH:14])[CH2:9]1)C1C=CC=CC=1>C(O)C.[C].[Pd]>[NH2:16][CH2:15][C:10]1([CH2:13][OH:14])[CH2:11][CH2:12][NH:8][CH2:9]1

Participants

4

Reactant 1

HCID 22903660HCID 22903660, compound

Product 1

HCID 22903668HCID 22903668, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

1-Benzyl-3-(benzylaminomethyl)-3-hydroxymethylpyrrolidine (2.0 g) was dissolved in ethanol (20 ml), and 10% palladium-carbon (1 g) was added. The mixture was hydrogenated under atmospheric pressure. After the completion of the reaction, the catalyst was removed, and the manure was concentrated to give the object compound as an oil.

Workup

  1. customAfter the completion of the reaction
  2. customthe catalyst was removed
  3. concentrationthe manure was concentrated

Sources & evidence

ORD record
ord-f9698094d94341da92d92dfd71cb66d2
Source dataset
uspto-grants-1997_10
Patent number
US05677316

Reaction notes

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